OR10X1

Across TCGA cell cohorts, OR10X1 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR10X1-associated genes across cancer lineages are CCL18, FHL5, and OR10H5. Each is linked with OR10X1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10X1-to-partner and partner-to-OR10X1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL18 grouped by OR10X1-low versus OR10X1-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10X1→partner) and Y-score (partner→OR10X1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	CCL18 →	+0.043	+4.672	<.001	.002	3	2
LUNG_SCLC	FHL5 →	+0.084	+2.824	<.001	.008	3	1
LUNG_SCLC	OR10H5 →	+0.047	+2.874	<.001	.007	3	1
LUNG_SCLC	CENPVL3 →	+0.791	+3.629	<.001	.003	3	1
LUNG_SCLC	GAGE12H →	+1.038	+3.392	.002	.001	3	1
LUNG_SCLC	TCP11X1 →	+0.449	+3.584	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

CCL18 by OR10X1 expression — BREAST

Explore this box plot interactively →