OR10W1

Across TCGA patient cohorts, OR10W1 mutation is significantly associated with the total protein of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10W1-associated genes across cancer lineages are Snail, ACC1, and INPP4B. Each is linked with OR10W1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10W1-to-partner and partner-to-OR10W1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Snail grouped by OR10W1-low versus OR10W1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10W1→partner) and Y-score (partner→OR10W1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Snail →	-0.179	-2.987	.013	.035	3	2
UCEC	ACC1 →	+0.292	+2.115	.032	.017	3	2
UCEC	INPP4B →	-0.365	-3.584	.002	.002	3	2
UCEC	STAT3_pY705 →	-0.381	-1.690	<.001	.042	3	2
UCEC	Tuberin_pT1462 →	+0.317	+2.009	<.001	.005	3	2
UCEC	4E-BP1 →	+0.248	+3.351	.014	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

Snail by OR10W1 expression — SKCM

Explore this box plot interactively →