Across TCGA patient cohorts, OR10T2 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10T2-associated genes across cancer lineages are NF2, Smac, and 4E-BP1_pT70. Each is linked with OR10T2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10T2-to-partner and partner-to-OR10T2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10T2→partner) and Y-score (partner→OR10T2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	NF2 →	+0.223	+2.321	.032	.032	3	1
SKCM	Smac →	+0.255	+2.182	.018	.033	3	1
SKCM	4E-BP1_pT70 →	-0.180	-3.152	.012	.017	3	1
SKCM	Chk2 →	+0.204	+2.321	.022	.033	3	1
UCEC	Lck →	+0.250	+2.459	.003	.019	3	1
UCEC	MIG-6 →	+0.102	+2.331	.015	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

OR10T2 survival (RNA) · tumor vs normal (RNA) · all OR10T2 data types