Across TCGA cell cohorts, OR10T2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR10T2-associated genes across cancer lineages are NPHS2, TRIM60, and OR8A1. Each is linked with OR10T2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10T2-to-partner and partner-to-OR10T2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10T2→partner) and Y-score (partner→OR10T2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	NPHS2 →	+0.013	+4.817	.002	.001	3	1
LUNG_SCLC	TRIM60 →	+0.005	+4.643	<.001	.004	3	1
LUNG_SCLC	OR8A1 →	+0.255	+4.044	.002	.009	3	1
LUNG_SCLC	LYPD2 →	+0.375	+4.269	.006	.005	3	1
SKIN	NEU2 →	+0.019	+3.977	<.001	.001	3	1
SKIN	PTPN5 →	+0.075	+3.765	.003	.006	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

OR10T2 survival (RNA) · tumor vs normal (RNA) · all OR10T2 data types