OR10Q1

Across TCGA patient cohorts, OR10Q1 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10Q1-associated genes across cancer lineages are TFRC, INPP4B, and p38-MAPK. Each is linked with OR10Q1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10Q1-to-partner and partner-to-OR10Q1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by OR10Q1-low versus OR10Q1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10Q1→partner) and Y-score (partner→OR10Q1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TFRC →	+0.746	+3.169	.001	.018	3	2
SKCM	INPP4B →	-0.178	-1.982	.038	.031	3	2
LUAD	p38-MAPK →	-0.204	-2.983	.020	.036	3	1
LUAD	AMPK_pT172 →	-0.663	-3.000	<.001	.035	3	1
LUSC	Acetyl-a-Tubulin-Lys40 →	+0.801	+3.169	.001	.017	3	1
LUSC	p27_pT157 →	+0.090	+2.844	.009	.032	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

TFRC by OR10Q1 expression — UCEC

Explore this box plot interactively →