OR10Q1

Across TCGA cell cohorts, OR10Q1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR10Q1-associated genes across cancer lineages are NPHS2, C20orf85, and GH2. Each is linked with OR10Q1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10Q1-to-partner and partner-to-OR10Q1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NPHS2 grouped by OR10Q1-low versus OR10Q1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10Q1→partner) and Y-score (partner→OR10Q1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NPHS2 →	+0.077	+4.029	.006	.009	3	1
LARGE_INTESTINE	C20orf85 →	+0.167	+4.054	.004	.004	3	1
LUNG_NSCLC_LUAD	GH2 →	+0.056	+3.544	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR6B3 →	+0.023	+3.734	<.001	.006	3	1
LUNG_NSCLC_LUAD	OR5M10 →	+0.011	+4.078	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

NPHS2 by OR10Q1 expression — LARGE_INTESTINE

Explore this box plot interactively →