OR10P1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR10P1 mutation is significantly associated with the RNA expression of many other genes, with 1,362 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10P1-associated genes across cancer lineages are HIRIP3, PSMG3, and SNRNP25. Each is linked with OR10P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10P1-to-partner and partner-to-OR10P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HIRIP3 grouped by OR10P1-low versus OR10P1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10P1→partner) and Y-score (partner→OR10P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECHIRIP3 →+0.419+2.098.006.00332
UCECPSMG3 →+0.457+2.606<.001<.00132
UCECSNRNP25 →+0.510+3.595<.001.00132
UCECRNF25 →+0.300+2.638.005.00532
UCECMON1A →+0.380+2.595<.001.00532
UCECDEPP1 →-0.761-3.584.002.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,362 associations by consensus.

HIRIP3 by OR10P1 expression — UCEC

Box plot of HIRIP3 in OR10P1-low vs OR10P1-high samples in UCEC.

Explore this box plot interactively →

Exploration