OR10K1

Across TCGA patient cohorts, OR10K1 mutation is significantly associated with the RNA expression of many other genes, with 3,335 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10K1-associated genes across cancer lineages are H2AZ1, LINC01038, and RN7SKP100. Each is linked with OR10K1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR10K1-to-partner and partner-to-OR10K1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H2AZ1 grouped by OR10K1-low versus OR10K1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10K1→partner) and Y-score (partner→OR10K1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	H2AZ1 →	+0.586	+3.202	.003	<.001	3	3
LUAD	LINC01038 →	+0.054	+4.117	<.001	.005	3	3
LUSC	RN7SKP100 →	+0.242	+3.200	<.001	.002	3	3
UCEC	SLC7A5 →	+0.767	+2.592	.009	.006	3	3
STAD	RAB28P4 →	+0.094	+3.811	<.001	.001	3	3
UCEC	INCENP →	+0.629	+2.042	.004	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,335 associations by consensus.

H2AZ1 by OR10K1 expression — UCEC

Explore this box plot interactively →