OR10K1

Across TCGA cell cohorts, OR10K1 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR10K1-associated genes across cancer lineages are MS4A15, LALBA, and SOX14. Each is linked with OR10K1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10K1-to-partner and partner-to-OR10K1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A15 grouped by OR10K1-low versus OR10K1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10K1→partner) and Y-score (partner→OR10K1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	MS4A15 →	+0.307	+3.684	<.001	.009	3	1
SOFT_TISSUE	LALBA →	+1.235	+3.882	<.001	.004	3	1
SOFT_TISSUE	SOX14 →	+0.740	+3.882	<.001	.004	3	1
SOFT_TISSUE	FTMT →	+0.052	+4.392	<.001	.004	3	1
SOFT_TISSUE	CLEC4G →	+0.045	+3.635	.001	.007	3	1
SOFT_TISSUE	AADACL3 →	+0.009	+4.169	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

MS4A15 by OR10K1 expression — SOFT_TISSUE

Explore this box plot interactively →