OR10J5

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR10J5 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10J5-associated genes across cancer lineages are MIG-6, PCNA, and EGFR_pY1068. Each is linked with OR10J5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10J5-to-partner and partner-to-OR10J5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10J5→partner) and Y-score (partner→OR10J5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIG-6 →+0.112+3.598.019.00132
UCECPCNA →+0.235+2.321.024.03432
UCECEGFR_pY1068 →-0.254-2.459.036.02031
UCECNotch1 →+0.264+2.331<.001.01931
UCECPKC-b-II_pS660 →-0.318-2.459.017.02031
UCECRAD51 →+0.133+2.459.048.02031
Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

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