OR10J3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR10J3 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR10J3-associated genes across cancer lineages are PRAMEF11, RSPH6A, and GALR3. Each is linked with OR10J3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10J3-to-partner and partner-to-OR10J3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10J3→partner) and Y-score (partner→OR10J3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCPRAMEF11 →+0.026+5.029<.001.00631
LARGE_INTESTINERSPH6A →+0.103+3.466.004.00531
LARGE_INTESTINEGALR3 →+0.084+3.602.007.00531
LARGE_INTESTINEBRDT →+0.096+3.555<.001.00331
LARGE_INTESTINEPTH2R →+0.851+2.716<.001.00931
LARGE_INTESTINESAXO1 →+0.037+3.819.005.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

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