OR10H5

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR10H5 mutation is significantly associated with the RNA expression of many other genes, with 1,422 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10H5-associated genes across cancer lineages are CHAF1A, RNA5SP71, and ANKRD49P4. Each is linked with OR10H5 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR10H5-to-partner and partner-to-OR10H5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHAF1A grouped by OR10H5-low versus OR10H5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10H5→partner) and Y-score (partner→OR10H5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCHAF1A →+0.577+2.191.001.00233
LUADRNA5SP71 →+0.370+3.745<.001.00532
LUADANKRD49P4 →+0.068+4.197<.001.00932
LUADHSPA8P17 →+0.027+4.197.007.00932
COADRNU6-468P →+0.137+3.973.006.00832
COADRNU6-709P →+0.144+3.973<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,422 associations by consensus.

CHAF1A by OR10H5 expression — UCEC

Box plot of CHAF1A in OR10H5-low vs OR10H5-high samples in UCEC.

Explore this box plot interactively →

Exploration