OR10H5

Across TCGA patient cohorts, OR10H5 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10H5-associated genes across cancer lineages are PCNA, Rab25, and C-Raf. Each is linked with OR10H5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10H5-to-partner and partner-to-OR10H5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by OR10H5-low versus OR10H5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10H5→partner) and Y-score (partner→OR10H5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.176	+1.584	.037	.036	3	2
UCEC	Rab25 →	-0.299	-2.321	.021	.033	3	2
UCEC	C-Raf →	+0.176	+2.502	.001	.002	3	2
SKCM	eEF2 →	+0.505	+3.169	.004	.019	3	1
SKCM	GSK3-a-b →	+0.167	+3.169	.049	.019	3	1
UCEC	14-3-3_beta →	-0.081	-1.847	.040	.049	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

PCNA by OR10H5 expression — UCEC

Explore this box plot interactively →