OR10H5

Across TCGA cell cohorts, OR10H5 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR10H5-associated genes across cancer lineages are PGLYRP3, PRAMEF10, and PRAMEF17. Each is linked with OR10H5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10H5-to-partner and partner-to-OR10H5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PGLYRP3 grouped by OR10H5-low versus OR10H5-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10H5→partner) and Y-score (partner→OR10H5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	PGLYRP3 →	+0.149	+3.523	<.001	.008	3	1
LUNG_SCLC	PRAMEF10 →	+0.708	+4.058	<.001	.007	3	1
LUNG_SCLC	PRAMEF17 →	+0.008	+4.058	<.001	.007	3	1
LUNG_SCLC	PRAMEF14 →	+0.219	+3.523	<.001	.008	3	1
LARGE_INTESTINE	GFRA4 →	+0.023	+3.930	<.001	.003	3	1
LARGE_INTESTINE	KRT85 →	+0.512	+3.823	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

PGLYRP3 by OR10H5 expression — LUNG_SCLC

Explore this box plot interactively →