OR10H4

Across TCGA pan-cancer cohorts, OR10H4 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated OR10H4 data layer compared with 8 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher OR10H4 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR10H4 expression acts as an unfavorable survival marker, although some lineages such as LUSC show a favorable association.

LIHC, LUSC, and SKCM are the cancer types where OR10H4 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	III,IV	0.270	0.732	.021	12	view →
LUSC	DFS	Median	All	1.000	0.369	.042	3	view →
SKCM	DFS	Median	All	0.103	0.214	.038	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

OR10H4–LIHC (OS)

Open the LIHC breakdown →