OR10H3

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, OR10H3 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated OR10H3 data layer compared with 12 for mass-spec protein.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher OR10H3 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR10H3 expression acts as an unfavorable survival marker.

DLBC are the cancer types where OR10H3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
DLBCOSMedianAll0.0540.842<.00112view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

OR10H3–DLBC (OS)

Kaplan–Meier survival curve for OR10H3 mutant vs wild-type samples in DLBC.

Open the DLBC breakdown →

Exploration