OR10H3

Across TCGA cell cohorts, OR10H3 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR10H3-associated genes across cancer lineages are STOML3, SLC13A2, and OR7D4. Each is linked with OR10H3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10H3-to-partner and partner-to-OR10H3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STOML3 grouped by OR10H3-low versus OR10H3-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10H3→partner) and Y-score (partner→OR10H3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	STOML3 →	+0.006	+4.807	<.001	.006	3	1
BLOOD_Myeloma	SLC13A2 →	+0.013	+4.807	<.001	.006	3	1
SOFT_TISSUE	OR7D4 →	+0.030	+5.977	<.001	.001	3	1
BLOOD_Lymphoma	FAM25C →	+0.351	+5.209	<.001	.005	3	1
CNS	GP9 →	+0.019	+4.754	<.001	.005	3	1
LARGE_INTESTINE	TMCO5A →	+0.019	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

STOML3 by OR10H3 expression — BLOOD_Myeloma

Explore this box plot interactively →