OR10H1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR10H1 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10H1-associated genes across cancer lineages are Caspase-7-cleavedD198, PCNA, and Rad50. Each is linked with OR10H1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR10H1-to-partner and partner-to-OR10H1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10H1→partner) and Y-score (partner→OR10H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADCaspase-7-cleavedD198 →+1.167+2.815.007.03633
UCECPCNA →+0.230+3.700.022.00123
UCECRad50 →-0.315-3.000.005.03632
UCECATM →-0.634-3.321.002.01032
UCECmTOR_pS2448 →-0.201-3.150.003.01922
UCECNotch1 →+0.227+3.335<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

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