OR10G9

Across TCGA patient cohorts, OR10G9 mutation is significantly associated with the RNA expression of many other genes, with 1,226 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10G9-associated genes across cancer lineages are DUTP3, E2F6P2, and TRIP4. Each is linked with OR10G9 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR10G9-to-partner and partner-to-OR10G9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DUTP3 grouped by OR10G9-low versus OR10G9-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10G9→partner) and Y-score (partner→OR10G9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DUTP3 →	+0.062	+5.011	<.001	.002	3	3
HNSC	E2F6P2 →	+0.051	+5.303	<.001	.006	3	2
UCEC	TRIP4 →	+0.609	+2.617	<.001	.006	3	2
UCEC	SLC35B1 →	+0.432	+2.606	.005	.006	3	2
UCEC	ATP6V1E1 →	+0.427	+3.711	.003	<.001	3	2
UCEC	SNRPA1 →	+0.477	+2.606	.003	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,226 associations by consensus.

DUTP3 by OR10G9 expression — LUAD

Explore this box plot interactively →