OR10G9

Across TCGA patient cohorts, OR10G9 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10G9-associated genes across cancer lineages are p90 RSK, MEK1, and p27_pT198. Each is linked with OR10G9 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10G9-to-partner and partner-to-OR10G9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p90 RSK grouped by OR10G9-low versus OR10G9-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10G9→partner) and Y-score (partner→OR10G9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	p90 RSK →	+0.180	+3.000	.049	.034	3	2
UCEC	MEK1 →	+0.489	+3.321	.010	.010	3	1
UCEC	p27_pT198 →	+0.115	+3.000	.041	.036	3	1
SKCM	mTOR →	+0.216	+2.115	.039	.018	3	1
SKCM	JNK_pT183_Y185 →	-0.122	-3.000	.038	.035	2	1
UCEC	ACC_pS79 →	+0.475	+3.321	.008	.010	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

p90 RSK by OR10G9 expression — SKCM

Explore this box plot interactively →