OR10G7

Across TCGA patient cohorts, OR10G7 mutation is significantly associated with the RNA expression of many other genes, with 3,319 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10G7-associated genes across cancer lineages are PUS3, MARCKSL1P2, and FCER1A. Each is linked with OR10G7 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR10G7-to-partner and partner-to-OR10G7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PUS3 grouped by OR10G7-low versus OR10G7-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10G7→partner) and Y-score (partner→OR10G7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	PUS3 →	+0.335	+3.223	.005	.009	3	3
UCEC	MARCKSL1P2 →	+0.225	+2.329	<.001	.005	3	3
UCEC	FCER1A →	-0.759	-3.406	.006	.005	3	3
UCEC	C19orf54 →	+0.429	+2.625	.001	.005	3	3
UCEC	DAXX →	+0.398	+3.362	.004	.005	3	3
SKCM	AURKA →	+0.738	+2.845	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,319 associations by consensus.

PUS3 by OR10G7 expression — LUSC

Explore this box plot interactively →