OR10G7

Across TCGA cell cohorts, OR10G7 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR10G7-associated genes across cancer lineages are RFPL3, CST9, and ECE2. Each is linked with OR10G7 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10G7-to-partner and partner-to-OR10G7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RFPL3 grouped by OR10G7-low versus OR10G7-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10G7→partner) and Y-score (partner→OR10G7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	RFPL3 →	+0.055	+3.868	.004	.002	3	1
OVARY	CST9 →	+0.006	+5.807	<.001	.001	3	1
LARGE_INTESTINE	ECE2 →	+0.360	+4.054	<.001	.004	3	1
LARGE_INTESTINE	CENPVL3 →	+0.329	+3.920	<.001	.005	3	1
SKIN	GOLGA6C →	+0.062	+3.617	.003	.004	3	1
SKIN	H3-4 →	+0.185	+3.722	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

RFPL3 by OR10G7 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →