OR10G4

Across TCGA pan-cancer cohorts, OR10G4 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated OR10G4 data layer compared with 6 for mutation status.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher OR10G4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR10G4 expression acts as an unfavorable survival marker, although some lineages such as OV and COAD show a favorable association.

STAD, UCS, and SKCM are the cancer types where OR10G4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Tertile	All	0.400	0.702	<.001	117	view →
UCS	OS	Tertile	All	0.165	0.697	<.001	108	view →
SKCM	DFS	Tertile	III,IV	0.058	0.648	.001	84	view →
KIRP	OS	Tertile	II,III,IV	0.161	0.771	.002	63	view →
UVM	OS	Tertile	All	0.218	0.696	.014	54	view →
GBM	DFS	Tertile	All	0.092	0.266	<.001	45	view →
LIHC	OS	Tertile	II,III,IV	0.051	0.696	<.001	45	view →
KIRC	DFS	Tertile	III,IV	0.159	0.489	.033	42	view →
ACC	DFS	Tertile	All	0.137	0.771	<.001	39	view →
TGCT	DFS	Tertile	II,III,IV	0.051	0.955	<.001	36	view →
LUSC	DFS	Tertile	All	0.402	0.750	.027	36	view →
ESCA	DFS	Tertile	All	0.175	0.538	.008	36	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

OR10G4–STAD (OS)

Open the STAD breakdown →