OR10G3

Across TCGA cell cohorts, OR10G3 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR10G3-associated genes across cancer lineages are ELOA3DP, OR13G1, and OR6Q1. Each is linked with OR10G3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10G3-to-partner and partner-to-OR10G3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ELOA3DP grouped by OR10G3-low versus OR10G3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10G3→partner) and Y-score (partner→OR10G3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ELOA3DP →	+0.023	+4.273	.003	.006	3	1
LARGE_INTESTINE	OR13G1 →	+0.024	+4.415	<.001	.007	3	1
LARGE_INTESTINE	OR6Q1 →	+0.022	+5.022	<.001	.002	3	1
LUNG_NSCLC_LUAD	COX4I2 →	+0.095	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	TEX33 →	+0.036	+6.266	<.001	<.001	3	1
LUNG_NSCLC_LUAD	GOLGA6L6 →	+0.006	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

ELOA3DP by OR10G3 expression — LARGE_INTESTINE

Explore this box plot interactively →