OR10G2

Across TCGA patient cohorts, OR10G2 mutation is significantly associated with the RNA expression of many other genes, with 1,249 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10G2-associated genes across cancer lineages are MIR5787, RPL23AP82, and CIDECP1. Each is linked with OR10G2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10G2-to-partner and partner-to-OR10G2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR5787 grouped by OR10G2-low versus OR10G2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10G2→partner) and Y-score (partner→OR10G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR5787 →	+0.571	+6.215	<.001	.001	3	2
UCEC	RPL23AP82 →	+0.683	+3.818	<.001	<.001	3	2
UCEC	CIDECP1 →	+0.418	+3.544	<.001	.002	3	2
UCEC	IFRD2 →	+0.516	+3.213	.005	.009	3	2
UCEC	RNU2-51P →	+0.558	+2.833	<.001	<.001	3	2
UCEC	RNA5SP155 →	+0.452	+2.051	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,249 associations by consensus.

MIR5787 by OR10G2 expression — BRCA

Explore this box plot interactively →