OR10G2

Across TCGA cell cohorts, OR10G2 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR10G2-associated genes across cancer lineages are OR4D2, PF4V1, and TBC1D21. Each is linked with OR10G2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10G2-to-partner and partner-to-OR10G2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4D2 grouped by OR10G2-low versus OR10G2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10G2→partner) and Y-score (partner→OR10G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR4D2 →	+0.012	+5.569	<.001	.001	3	2
LARGE_INTESTINE	PF4V1 →	+0.338	+3.793	<.001	.007	3	1
LARGE_INTESTINE	TBC1D21 →	+0.012	+4.437	<.001	.004	3	1
LARGE_INTESTINE	OR6Q1 →	+0.018	+4.437	<.001	.004	3	1
SKIN	SHCBP1L →	+0.025	+3.345	<.001	.007	3	1
SKIN	C1QB →	+0.046	+3.196	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

OR4D2 by OR10G2 expression — BLOOD_Leukemia

Explore this box plot interactively →