Across TCGA cell cohorts, OR10C1 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR10C1-associated genes across cancer lineages are TMEM196, GPX5, and IL36A. Each is linked with OR10C1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10C1-to-partner and partner-to-OR10C1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10C1→partner) and Y-score (partner→OR10C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	TMEM196 →	+0.069	+4.017	<.001	.007	3	1
LARGE_INTESTINE	GPX5 →	+0.206	+4.273	.004	.006	3	1
LUNG_SCLC	IL36A →	+0.020	+4.643	<.001	.004	3	1
LUNG_SCLC	OR7G3 →	+0.047	+4.643	<.001	.004	3	1
LUNG_SCLC	OR1M1 →	+0.012	+4.643	<.001	.004	3	1
LUNG_SCLC	FAM25A →	+0.140	+4.643	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

OR10C1 survival (RNA) · tumor vs normal (RNA) · all OR10C1 data types