OR10AG1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR10AG1 mutation is significantly associated with the RNA expression of many other genes, with 4,148 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR10AG1-associated genes across cancer lineages are OIP5, TIPIN, and WDR62. Each is linked with OR10AG1 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR10AG1-to-partner and partner-to-OR10AG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OIP5 grouped by OR10AG1-low versus OR10AG1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10AG1→partner) and Y-score (partner→OR10AG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECOIP5 →+0.672+2.923.001<.00134
SKCMTIPIN →+0.488+1.912<.001.00134
LUADWDR62 →+0.783+2.620<.001.00534
LUADCDKN3 →+1.010+3.486<.001.00233
SKCMRBBP8 →+0.765+2.515<.001<.00133
LUADPSMD11 →+0.557+2.942<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,148 associations by consensus.

OIP5 by OR10AG1 expression — UCEC

Box plot of OIP5 in OR10AG1-low vs OR10AG1-high samples in UCEC.

Explore this box plot interactively →

Exploration