OR10AG1

Across TCGA patient cohorts, OR10AG1 mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10AG1-associated genes across cancer lineages are PCNA, 4E-BP1, and p62 Lck ligand. Each is linked with OR10AG1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR10AG1-to-partner and partner-to-OR10AG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by OR10AG1-low versus OR10AG1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10AG1→partner) and Y-score (partner→OR10AG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.306	+2.502	<.001	.002	3	3
UCEC	4E-BP1 →	+0.328	+2.489	.001	.010	3	3
LUAD	p62 Lck ligand →	+0.479	+2.338	.028	.019	3	2
UCEC	AR →	-0.368	-2.000	.012	.010	3	2
LUAD	Cyclin-E2 →	+0.149	+2.338	.019	.019	3	2
SKCM	MEK1_p_S217_S221 →	+0.189	+1.713	.031	.024	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

PCNA by OR10AG1 expression — UCEC

Explore this box plot interactively →