OR10AG1

Across TCGA cell cohorts, OR10AG1 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR10AG1-associated genes across cancer lineages are DRD3, HSFY2, and OR10W1. Each is linked with OR10AG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10AG1-to-partner and partner-to-OR10AG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DRD3 grouped by OR10AG1-low versus OR10AG1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10AG1→partner) and Y-score (partner→OR10AG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DRD3 →	+0.012	+4.977	<.001	.007	3	1
LARGE_INTESTINE	HSFY2 →	+0.023	+4.977	<.001	.007	3	1
LARGE_INTESTINE	OR10W1 →	+0.022	+4.977	<.001	.007	3	1
LARGE_INTESTINE	CD300H →	+0.052	+5.415	<.001	.004	3	1
LUNG_SCLC	TAAR5 →	+0.026	+5.643	<.001	.002	3	1
LUNG_SCLC	OR10K1 →	+0.467	+5.029	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

DRD3 by OR10AG1 expression — LARGE_INTESTINE

Explore this box plot interactively →