OR10A7

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR10A7 mutation is significantly associated with the RNA expression of many other genes, with 460 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR10A7-associated genes across cancer lineages are E2F6P1, RNU6-1113P, and SPTLC1P5. Each is linked with OR10A7 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR10A7-to-partner and partner-to-OR10A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, E2F6P1 grouped by OR10A7-low versus OR10A7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10A7→partner) and Y-score (partner→OR10A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECE2F6P1 →+0.046+4.437<.001.00533
HNSCRNU6-1113P →+0.285+5.357<.001.00132
COADSPTLC1P5 →+0.431+4.831<.001.00332
LUADMIR885 →+0.472+6.757<.001<.00132
LUADFAM243A →+0.055+4.730<.001.00532
UCECRNA5SP423 →+0.792+3.039.005.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 460 associations by consensus.

E2F6P1 by OR10A7 expression — UCEC

Box plot of E2F6P1 in OR10A7-low vs OR10A7-high samples in UCEC.

Explore this box plot interactively →

Exploration