OR10A7

Across TCGA patient cohorts, OR10A7 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR10A7-associated genes across cancer lineages are ACC1, Ku80, and MYH11. Each is linked with OR10A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10A7-to-partner and partner-to-OR10A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACC1 grouped by OR10A7-low versus OR10A7-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10A7→partner) and Y-score (partner→OR10A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ACC1 →	+0.369	+3.182	.007	.009	3	1
SKCM	Ku80 →	+0.344	+3.169	.005	.017	3	1
SKCM	MYH11 →	-0.956	-3.459	.013	.005	3	1
SKCM	p62 Lck ligand →	+0.457	+3.012	.008	.018	3	1
SKCM	AMPK_alpha →	+0.141	+3.321	.024	.009	3	1
SKCM	TFRC →	+0.677	+3.169	.006	.017	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

ACC1 by OR10A7 expression — SKCM

Explore this box plot interactively →