OR10A7

Across TCGA cell cohorts, OR10A7 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR10A7-associated genes across cancer lineages are MAGEB4, PPP1R3A, and HPGDS. Each is linked with OR10A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10A7-to-partner and partner-to-OR10A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by OR10A7-low versus OR10A7-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10A7→partner) and Y-score (partner→OR10A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	MAGEB4 →	+0.008	+4.437	<.001	.004	3	1
SKIN	PPP1R3A →	+0.032	+3.930	.004	.003	3	1
SKIN	HPGDS →	+0.059	+3.823	<.001	.006	3	1
SKIN	FOXI1 →	+0.041	+3.920	.001	.005	3	1
SKIN	CCER1 →	+0.038	+4.437	<.001	.004	3	1
LARGE_INTESTINE	MMP26 →	+0.033	+3.217	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

MAGEB4 by OR10A7 expression — SKIN

Explore this box plot interactively →