OR10A7

Across TCGA cell cohorts, OR10A7 mutation is significantly associated with the mutation status of many other genes, with 657 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR10A7-associated genes across cancer lineages are OR52N2, DENND5A, and ZBTB14. Each is linked with OR10A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10A7-to-partner and partner-to-OR10A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52N2 grouped by OR10A7-low versus OR10A7-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10A7→partner) and Y-score (partner→OR10A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR52N2 →	+3.532	+3.357	.005	.005	1	2
SKIN	DENND5A →	+4.117	+3.638	.002	.002	1	2
SKIN	ZBTB14 →	+3.947	+3.947	<.001	<.001	1	2
SKIN	INSRR →	+2.725	+3.222	.004	.004	1	2
SKIN	KLHL13 →	+2.725	+3.222	.004	.004	1	2
SKIN	NSUN2 →	+3.117	+3.117	.009	.009	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 657 associations by consensus.

OR52N2 by OR10A7 expression — SKIN

Explore this box plot interactively →