OR10A5

Across TCGA patient cohorts, OR10A5 mutation is significantly associated with the RNA expression of many other genes, with 1,420 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10A5-associated genes across cancer lineages are HARBI1, PDHX, and PKMYT1. Each is linked with OR10A5 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR10A5-to-partner and partner-to-OR10A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HARBI1 grouped by OR10A5-low versus OR10A5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10A5→partner) and Y-score (partner→OR10A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HARBI1 →	+0.450	+2.839	<.001	.001	3	3
UCEC	PDHX →	+0.448	+2.386	.009	.003	3	3
UCEC	PKMYT1 →	+0.850	+3.010	<.001	<.001	3	3
UCEC	FXR2 →	+0.490	+2.321	.003	.006	3	3
UCEC	PRPF4 →	+0.595	+2.343	<.001	.003	3	3
UCEC	GOLGA2 →	+0.486	+2.855	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,420 associations by consensus.

HARBI1 by OR10A5 expression — UCEC

Explore this box plot interactively →