OR10A5

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR10A5 RNA expression is significantly associated with the go_rna of many other GO terms, with 262 significant associations in total. CNS shows the largest number of these associations.

The most reproducible OR10A5-associated GO terms across cancer lineages are Negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage, Positive regulation of Golgi to plasma membrane protein transport, and Thalamus development. Each is linked with OR10A5 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR10A5-to-partner and partner-to-OR10A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage grouped by OR10A5-low versus OR10A5-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10A5→partner) and Y-score (partner→OR10A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaNegative regulation of intrinsic apoptotic signaling pathway in response to DNA damage →-0.053-0.013<.001.00233
PANCREASPositive regulation of Golgi to plasma membrane protein transport →+0.080+0.012.003.00333
BLOOD_MyelomaThalamus development →+0.156+0.050.005.00633
LARGE_INTESTINERegulation of intrinsic apoptotic signaling pathway by p53 class mediator →-0.058-0.011.008.00823
OVARYPostsynaptic actin cytoskeleton organization →-0.122-0.012.002.00232
BLOOD_LymphomaNeuron projection maintenance →-0.066-0.015.008.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 262 associations by consensus.

Negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by OR10A5 expression — BLOOD_Lymphoma

Box plot of Negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage in OR10A5-low vs OR10A5-high samples in BLOOD_Lymphoma.

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Exploration