OR10A5

Across TCGA cell cohorts, OR10A5 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR10A5-associated genes across cancer lineages are SPATA48, GAGE12E, and OR1D2. Each is linked with OR10A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10A5-to-partner and partner-to-OR10A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA48 grouped by OR10A5-low versus OR10A5-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10A5→partner) and Y-score (partner→OR10A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	SPATA48 →	+0.006	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	GAGE12E →	+0.076	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUAD	OR1D2 →	+0.026	+6.266	<.001	<.001	3	1
LUNG_NSCLC_LUAD	DPRX →	+0.283	+5.228	<.001	.005	3	1
SKIN	PAX4 →	+0.021	+4.882	<.001	<.001	3	1
SKIN	KLHL1 →	+0.012	+4.054	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

SPATA48 by OR10A5 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →