OR10A4

Across TCGA patient cohorts, OR10A4 mutation is significantly associated with the RNA expression of many other genes, with 514 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR10A4-associated genes across cancer lineages are RNA5SP281, LYST, and OR51T1. Each is linked with OR10A4 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR10A4-to-partner and partner-to-OR10A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP281 grouped by OR10A4-low versus OR10A4-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10A4→partner) and Y-score (partner→OR10A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP281 →	+0.070	+3.912	.008	.009	3	3
SKCM	LYST →	-1.009	-2.807	<.001	.003	3	2
HNSC	OR51T1 →	+0.029	+4.505	.001	.009	3	2
SKCM	RN7SL621P →	+0.067	+2.212	<.001	.003	3	2
SKCM	APOBEC3AP1 →	+0.083	+2.290	.005	.001	3	2
SKCM	LINC02420 →	+0.039	+2.495	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 514 associations by consensus.

RNA5SP281 by OR10A4 expression — LUAD

Explore this box plot interactively →