OR10A4

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR10A4 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR10A4-associated genes across cancer lineages are SCGB1D4, COX4I2, and TEX33. Each is linked with OR10A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10A4-to-partner and partner-to-OR10A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCGB1D4 grouped by OR10A4-low versus OR10A4-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10A4→partner) and Y-score (partner→OR10A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYSCGB1D4 →+0.130+5.807<.001.00131
LUNG_NSCLC_LUADCOX4I2 →+0.098+5.228<.001.00531
LUNG_NSCLC_LUADTEX33 →+0.036+6.266<.001<.00131
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

SCGB1D4 by OR10A4 expression — OVARY

Box plot of SCGB1D4 in OR10A4-low vs OR10A4-high samples in OVARY.

Explore this box plot interactively →

Exploration