OR10A3

Across TCGA patient cohorts, OR10A3 mutation is significantly associated with the RNA expression of many other genes, with 2,337 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10A3-associated genes across cancer lineages are KRTAP3-3, SLC25A1P3, and RNU6-927P. Each is linked with OR10A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10A3-to-partner and partner-to-OR10A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP3-3 grouped by OR10A3-low versus OR10A3-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10A3→partner) and Y-score (partner→OR10A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	KRTAP3-3 →	+0.427	+3.888	<.001	.004	3	2
LUAD	SLC25A1P3 →	+0.161	+4.127	<.001	.002	3	2
GBM	RNU6-927P →	+0.807	+5.352	<.001	.005	3	2
UCEC	DHRS2 →	+0.683	+2.021	.009	.001	3	2
UCEC	MTHFS →	+0.474	+3.186	.001	<.001	3	2
UCEC	ENPP2 →	-0.963	-3.079	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,337 associations by consensus.

KRTAP3-3 by OR10A3 expression — LUAD

Explore this box plot interactively →