OR10A3

Across TCGA cell cohorts, OR10A3 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR10A3-associated genes across cancer lineages are PTH2, OR52W1, and OR8A1. Each is linked with OR10A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10A3-to-partner and partner-to-OR10A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTH2 grouped by OR10A3-low versus OR10A3-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10A3→partner) and Y-score (partner→OR10A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PTH2 →	+0.162	+3.481	<.001	.004	3	1
LUNG_NSCLC_LUAD	OR52W1 →	+0.062	+3.906	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR8A1 →	+0.290	+3.628	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR8D1 →	+0.048	+3.343	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR8B8 →	+0.017	+4.149	.002	<.001	3	1
LUNG_NSCLC_LUAD	OR8G1 →	+0.087	+3.481	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

PTH2 by OR10A3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →