OPRL1

Across TCGA patient cohorts, OPRL1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,159 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible OPRL1-associated genes across cancer lineages are MYL9, LAMA4, and TTF2. Each is linked with OPRL1 in more than 3 cancer types. Because this analysis shows association rather than direction, both OPRL1-to-partner and partner-to-OPRL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OPRL1 versus MYL9 in GBM, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OPRL1→partner) and Y-score (partner→OPRL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MYL9 →	+0.944	+0.599	.005	.001	3	4
CCRCC	LAMA4 →	+0.572	+0.196	.004	.001	3	3
HNSC	TTF2 →	-0.407	-0.333	.007	.009	3	3
CCRCC	TMEM184B →	+0.352	+0.214	.005	.003	3	3
CCRCC	RNU6-1226P →	+0.985	+0.236	<.001	<.001	3	3
CCRCC	PPP1R3G →	+0.617	+0.212	.003	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,159 associations by consensus.

OPRL1 vs MYL9 — GBM

Explore this scatter interactively →