OPRK1

Across TCGA patient cohorts, OPRK1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,536 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible OPRK1-associated genes across cancer lineages are LINC00706, PIK3CG, and P2RX1. Each is linked with OPRK1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OPRK1-to-partner and partner-to-OPRK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OPRK1 versus LINC00706 in LUAD, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OPRK1→partner) and Y-score (partner→OPRK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC00706 →	+0.347	+0.635	<.001	<.001	3	3
UCEC	PIK3CG →	+0.967	+1.024	.009	<.001	3	3
LSCC	P2RX1 →	+1.123	+0.852	<.001	<.001	3	3
UCEC	VNN2 →	+1.966	+0.891	.008	.006	3	3
LUAD	PCBD2 →	-0.547	-0.608	<.001	<.001	3	3
UCEC	MS4A1 →	+1.496	+0.898	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,536 associations by consensus.

OPRK1 vs LINC00706 — LUAD

Explore this scatter interactively →