OPRK1

Across TCGA cell cohorts, OPRK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 460 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible OPRK1-associated GO terms across cancer lineages are Establishment of protein localization to organelle, Protein-RNA complex organization, and Aerobic respiration. Each is linked with OPRK1 in more than 7 cancer types. Because this analysis shows association rather than direction, both OPRK1-to-partner and partner-to-OPRK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to organelle grouped by OPRK1-low versus OPRK1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OPRK1→partner) and Y-score (partner→OPRK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Establishment of protein localization to organelle →	+0.027	+0.965	.005	.008	1	8
LUNG_SCLC	Protein-RNA complex organization →	+0.060	+1.440	<.001	.001	3	5
OESOPHAGUS	Aerobic respiration →	+0.141	+0.306	<.001	.008	3	4
OVARY	Regulation of RNA stability →	+0.031	+0.121	.001	.001	2	5
LUNG_NSCLC_LUAD	Regulation of mRNA catabolic process →	+0.030	+0.136	<.001	.002	2	5
OVARY	Regulation of cell cycle G1/S phase transition →	+0.043	+0.175	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 460 associations by consensus.

Establishment of protein localization to organelle by OPRK1 expression — LUNG_SCLC

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