OPN1SW

Across TCGA patient cohorts, OPN1SW protein abundance is significantly associated with the RNA expression of many other genes, with 4,373 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible OPN1SW-associated genes across cancer lineages are CENPE, SEC14L2, and PROCR. Each is linked with OPN1SW in more than 2 cancer types. Because this analysis shows association rather than direction, both OPN1SW-to-partner and partner-to-OPN1SW results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OPN1SW versus CENPE in BRCA, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OPN1SW→partner) and Y-score (partner→OPN1SW) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CENPE →	+0.964	+1.291	<.001	<.001	3	3
BRCA	SEC14L2 →	-1.175	-1.167	<.001	<.001	3	2
UCEC	PROCR →	-0.780	-0.828	.002	.003	3	2
BRCA	CST3 →	-0.743	-0.777	.005	.001	3	2
UCEC	JHY →	-1.339	-1.083	.005	.004	3	2
UCEC	B3GAT1 →	-1.065	-0.855	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,373 associations by consensus.

OPN1SW vs CENPE — BRCA

Explore this scatter interactively →