OPN1SW

Across TCGA patient cohorts, OPN1SW protein abundance is significantly associated with the protein abundance of many other proteins, with 8,363 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible OPN1SW-associated proteins across cancer lineages are TRPS1_S90, TRPS1, and TRPS1_S1066. Each is linked with OPN1SW in more than 3 cancer types. Because this analysis shows association rather than direction, both OPN1SW-to-partner and partner-to-OPN1SW results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OPN1SW versus TRPS1_S90 in LSCC, with a Pearson correlation of 0.84.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OPN1SW→partner) and Y-score (partner→OPN1SW) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TRPS1_S90 →	+1.300	+1.793	<.001	<.001	3	4
BRCA	TRPS1 →	+0.668	+1.010	<.001	<.001	3	4
LSCC	TRPS1_S1066 →	+1.688	+1.812	<.001	<.001	3	4
BRCA	RBBP5_S497 →	+1.109	+1.091	<.001	<.001	3	3
HNSC	TRPS1_T751 →	+1.037	+0.968	<.001	<.001	3	3
UCEC	UBA1_S835 →	+0.776	+0.994	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,363 associations by consensus.

OPN1SW vs TRPS1_S90 — LSCC

Explore this scatter interactively →