OPN1SW

Across TCGA cell cohorts, OPN1SW mutation is significantly associated with the mutation status of many other genes, with 742 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OPN1SW-associated genes across cancer lineages are SORBS3, PIK3CA, and ARMC7. Each is linked with OPN1SW in more than 1 cancer types. Because this analysis shows association rather than direction, both OPN1SW-to-partner and partner-to-OPN1SW results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SORBS3 grouped by OPN1SW-low versus OPN1SW-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OPN1SW→partner) and Y-score (partner→OPN1SW) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SORBS3 →	+4.000	+5.050	.008	.008	1	2
BLOOD_Leukemia	PIK3CA →	+4.000	+5.050	.008	.008	1	2
BLOOD_Leukemia	ARMC7 →	+4.321	+5.285	.005	.005	1	2
BLOOD_Leukemia	PALMD →	+5.321	+5.894	.002	.002	1	2
BLOOD_Leukemia	TBC1D10A →	+4.321	+5.285	.005	.005	1	2
BLOOD_Leukemia	SMAD7 →	+4.321	+5.285	.005	.005	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 742 associations by consensus.

SORBS3 by OPN1SW expression — BLOOD_Leukemia

Explore this box plot interactively →