OPN1MW

Across TCGA pan-cancer cohorts, OPN1MW RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated OPN1MW data layer compared with 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher OPN1MW RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OPN1MW expression acts as an unfavorable survival marker.

LUAD, STAD, and PAAD are the cancer types where OPN1MW RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.098	0.791	<.001	54	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	33	view →
PAAD	OS	Tertile	II,III,IV	0.210	0.556	.007	9	view →
UCEC	DFS	Tertile	All	0.362	0.652	.038	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

OPN1MW–LUAD (DFS)

Open the LUAD breakdown →