OPN1MW

Across TCGA pan-cancer cohorts, OPN1MW Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated OPN1MW data layer compared with 4 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher OPN1MW Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OPN1MW expression acts as an unfavorable survival marker.

SKCM and LUSC are the cancer types where OPN1MW Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	II,III,IV	0.072	0.843	<.001	24	view →
LUSC	OS	Median	All	0.005	0.776	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

OPN1MW–SKCM (OS)

Open the SKCM breakdown →