OPLAH

Across TCGA patient cohorts, OPLAH RNA expression is significantly associated with the protein abundance of many other proteins, with 10,105 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible OPLAH-associated proteins across cancer lineages are OPLAH_T151, SCRIB, and NECAP2. Each is linked with OPLAH in more than 8 cancer types. Because this analysis shows association rather than direction, both OPLAH-to-partner and partner-to-OPLAH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OPLAH versus OPLAH_T151 in BRCA, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OPLAH→partner) and Y-score (partner→OPLAH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OPLAH_T151 →	+1.179	+0.939	<.001	.001	3	9
OV	SCRIB →	+0.414	+1.222	<.001	<.001	3	5
LSCC	NECAP2 →	-0.265	-0.834	<.001	.001	3	4
OV	PYCR3 →	+0.398	+1.131	<.001	<.001	3	4
BRCA	HGH1 →	+0.303	+0.782	<.001	.003	3	4
LSCC	BOP1 →	+0.304	+0.590	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,105 associations by consensus.

OPLAH vs OPLAH_T151 — BRCA

Explore this scatter interactively →